🕑 6 min read · Reviewed by the Adderall Mart content team · Updated August 2026
Strattera vs Adderall at a glance
| Strattera | Adderall |
|---|
| Active ingredient | Atomoxetine | Amphetamine salts |
| Type | Non-stimulant | Stimulant |
| Schedule | Not a controlled substance | Controlled substance |
| How it works | Raises norepinephrine | Raises dopamine & norepinephrine |
| Onset of effect | Takes weeks to build | Fast |
| Abuse potential | Low | Higher |
How they work
Adderall is a stimulant that quickly raises dopamine and norepinephrine in the brain, giving most people fast relief of ADHD symptoms. Strattera (atomoxetine) works differently — it selectively raises norepinephrine and builds up its effect gradually over a few weeks, rather than acting within minutes.
Why choose a non-stimulant?
Some people can't tolerate stimulants, have heart conditions, or have a history of substance misuse, so a non-stimulant like Strattera is sometimes preferred. Because Strattera is not a controlled substance, it may also be easier to obtain and refill. The trade-off is that it takes longer to work and some people don't respond as strongly.
Side effects
Adderall commonly reduces appetite, disturbs sleep and raises heart rate. Strattera can cause nausea, dry mouth, drowsiness, reduced appetite and, in rare cases, changes in mood or blood pressure. Both require close monitoring by a doctor.
Which to choose?
For many people, a stimulant is the first-line choice because it acts quickly. A non-stimulant like Strattera is an option when stimulants aren't suitable. Your clinician will weigh your symptoms, health history and preferences. There is no single best medication — treatment is personalised.
Frequently asked questions
Is Strattera a stimulant?
No. Strattera is a non-stimulant ADHD medication, while Adderall is a stimulant.
How fast does Strattera work?
Unlike Adderall, Strattera builds up its effect over several weeks and is not an immediate treatment.
Can I take Strattera and Adderall together?
Sometimes a clinician may use a combination, but only under close supervision. Never combine them on your own.
Related products
For reference, see our informational pages on Adderall, Vyvanse, Ritalin and Strattera. Always use ADHD medication under a doctor's care and with a valid prescription.
This content is for educational purposes only and is not medical advice. Always consult a licensed physician or pharmacist before starting, stopping or changing any medication.
